{"id":1474261,"date":"2024-06-29T12:10:00","date_gmt":"2024-06-29T16:10:00","guid":{"rendered":"https:\/\/bugaluu.com\/news\/?p=1474261"},"modified":"2024-06-29T12:10:00","modified_gmt":"2024-06-29T16:10:00","slug":"customized-b-vitamin-therapy-could-help-parkinsons-patients-new-study-suggests","status":"publish","type":"post","link":"https:\/\/bugaluu.com\/news\/customized-b-vitamin-therapy-could-help-parkinsons-patients-new-study-suggests\/1474261\/","title":{"rendered":"Customized B Vitamin Therapy Could Help Parkinson\u2019s Patients, New Study Suggests"},"content":{"rendered":"<p><span class=\"field field--name-title field--type-string field--label-hidden\">Customized B Vitamin Therapy Could Help Parkinson\u2019s Patients, New Study Suggests<\/span><\/p>\n<div class=\"clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item\">\n<p><em><a href=\"https:\/\/www.theepochtimes.com\/health\/customized-b-vitamin-therapy-could-help-parkinsons-patients-new-study-suggests-5672890?utm_source=partner&amp;utm_campaign=ZeroHedge&amp;src_src=partner&amp;src_cmp=ZeroHedge\">Authored by George Citroner via The Epoch Times<\/a> (emphasis ours),<\/em><\/p>\n<p>A team of Japanese scientists has uncovered an unexpected link between the gut and the brain. The discovery may offer fresh insights into managing a condition that affects 9 million people worldwide.<\/p>\n<p><a href=\"https:\/\/cms.zerohedge.com\/s3\/files\/inline-images\/image_92%28752%29.jpg?itok=RGJVTc5Y\"><\/a><\/p>\n<h2>Deficiency of 2 B Vitamins Linked to Parkinson\u2019s<\/h2>\n<p>The study, published in <a href=\"https:\/\/www.nature.com\/articles\/s41531-024-00724-z\">npj Parkinson\u2019s Disease<\/a>, suggests that vitamin B deficiency may contribute to Parkinson\u2019s development by compromising the intestinal barrier, which typically prevents toxins from entering the bloodstream. Toxins in the bloodstream may lead to neuroinflammation, which is inflammation in the nervous system often associated with neurodegenerative diseases and other neurological conditions.<\/p>\n<p>Researchers used <a href=\"https:\/\/www.csus.edu\/indiv\/r\/rogersa\/bio181\/seqshotgun.pdf\">shotgun sequencing<\/a> to analyze stool samples, allowing them to identify changes in the microbial community and genetic makeup. The study found fewer genes in Parkinson\u2019s patients\u2019 gut bacteria responsible for making vitamins B2 (riboflavin) and B7 (biotin). Both have anti-inflammatory properties and may help counteract the neuroinflammation associated with Parkinson\u2019s disease.<\/p>\n<p>This suggests that B vitamin supplementation could potentially relieve Parkinson\u2019s symptoms and even slow disease progression, Hiroshi Nishiwaki, the lead study author, said in a press release.<\/p>\n<p><a href=\"https:\/\/www.scielo.br\/j\/bjmbr\/a\/BM4WLJBtjxF8Cx3wFsjFhKb\/?lang=en\">Previous research<\/a> has already shown that high doses of riboflavin contribute to the recovery of some motor functions in Parkinson\u2019s patients. While there\u2019s no specific research on biotin supplementation for Parkinson\u2019s, <a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0028390815300733?via%3Dihub\">one study<\/a> found that high doses of biotin improved symptoms in patients with multiple sclerosis, another neurological disorder.<\/p>\n<h2>Customized for Individual Microbiomes<\/h2>\n<p>The findings also suggest that vitamin therapy could potentially be customized based on each patient\u2019s unique microbiome profile to delay the onset of Parkinson\u2019s-associated symptoms.<\/p>\n<p>\u201cWe could perform gut microbiota analysis on patients or conduct fecal metabolite analysis,\u201d Mr. Nishiwaki said in the press release.\u201c We could identify individuals with specific deficiencies and administer oral riboflavin and biotin supplements to those with decreased levels, potentially creating an effective treatment,\u201d he added.<\/p>\n<p>The study demonstrates the importance of the gut microbiome in the progression and initiation of Parkinson\u2019s disease, a theory first hypothesized more than 20 years ago, Dr. Raminder Parihar, the director of neuromodulation at the Montefiore Neurological Surgery Movement Disorders Center who was not affiliated with the study, told The Epoch Times.<\/p>\n<p>\u201cThis provides another avenue that should be further explored on using supplementation of riboflavin and biotin to slow the progression of Parkinson\u2019s disease and potentially prevent the development of motor symptoms in Parkinson\u2019s disease,\u201d Dr. Parihar added.<\/p>\n<h2>Other Vitamins That Could Help<\/h2>\n<p>While no vitamins or nutrients can cure Parkinson\u2019s disease, several may help alleviate symptoms or reduce risk. They include:<\/p>\n<p><strong>Vitamin D:<\/strong> may <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35334877\/\">reduce the risk<\/a> of developing the condition<br \/>\n\t<strong>Omega-3 fatty acids:<\/strong> <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6747747\/\">anti-inflammatory<\/a>; found in fatty fish, flaxseeds, and walnuts<br \/>\n\t<strong>Vitamin E:<\/strong> antioxidant that <a href=\"https:\/\/www.frontiersin.org\/journals\/nutrition\/articles\/10.3389\/fnut.2023.1289238\/full\">may protect against<\/a> neurodegeneration and reduce oxidative stress<br \/>\n\t<strong>Magnesium:<\/strong> may alleviate symptoms like <a href=\"https:\/\/parkinsonseurope.org\/2018\/09\/26\/magnesium-muscles-parkinsons\/#:~:text=Recent%20research%20has%20suggested%20that,of%20processes%20throughout%20our%20bodies.\">muscle cramps<\/a> and rigidity<br \/>\n\t<strong>B vitamins:<\/strong> B12 supplementation may <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7019700\/\">help with fatigue<\/a> and <a href=\"https:\/\/www.cambridge.org\/core\/journals\/international-psychogeriatrics\/article\/abs\/cognitive-impairment-and-vitamin-b12-a-review\/2EE3400E317E7C82300369F195A7FEBD\">cognitive decline<\/a><br \/>\n\t<strong>N-acetylcysteine (NAC):<\/strong> linked to <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31206613\/\">dopaminergic improvement<\/a> and reduced <a href=\"https:\/\/www.mdpi.com\/2076-3921\/10\/6\/967\">oxidative stress and inflammation<\/a><br \/>\n\t<strong>Curcumin:<\/strong> found in turmeric; <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9199586\/\">may protect<\/a> dopamine-producing neurons<br \/>\n\t<strong>Resveratrol:<\/strong> found in grapes, berries, and peanuts; may reduce <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35013904\/\">oxidative stress<\/a><br \/>\n\t<strong>Selenium:<\/strong> higher blood levels <a href=\"https:\/\/link.springer.com\/article\/10.1007\/s11356-023-30337-7\">associated with<\/a> reduced Parkinson\u2019s risk<\/p>\n<p>Dr. Parihar noted that some vitamins may interfere with levodopa, a drug <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK482140\/#:~:text=Levodopa%20is%20typically%20prescribed%20to,due%20to%20carbon%20monoxide%20intoxication.\">commonly prescribed<\/a> to Parkinson\u2019s patients. Iron, for example, can affect the absorption of levodopa\u00a0if taken simultaneously. He recommends taking iron supplements an hour after levodopa to allow for proper absorption.<\/p>\n<p>Consult a health care professional before starting any supplements, as they may interact with medications or have side effects. While these vitamins and nutrients show potential benefits, they should not replace standard medical treatment for Parkinson\u2019s disease.<\/p>\n<\/div>\n<p>      <span class=\"field field--name-uid field--type-entity-reference field--label-hidden\"><a title=\"View user profile.\" href=\"https:\/\/cms.zerohedge.com\/users\/tyler-durden\" class=\"username\">Tyler Durden<\/a><\/span><br \/>\n<span class=\"field field--name-created field--type-created field--label-hidden\">Sat, 06\/29\/2024 &#8211; 08:10<\/span><\/p>\n<p>\u200b<a href=\"https:\/\/www.zerohedge.com\/medical\/customized-b-vitamin-therapy-could-help-parkinsons-patients-new-study-suggests\" target=\"_blank\" class=\"\" rel=\"noopener\">https:\/\/www.zerohedge.com\/medical\/customized-b-vitamin-therapy-could-help-parkinsons-patients-new-study-suggests<\/a>\u00a0<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Customized B Vitamin Therapy Could Help Parkinson\u2019s Patients, New Study Suggests Authored by George Citroner via The Epoch Times (emphasis ours), A team of Japanese&#8230;<\/p>\n","protected":false},"author":0,"featured_media":1474262,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_post_was_ever_published":false},"categories":[1],"tags":[],"class_list":["post-1474261","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news","wpcat-1-id"],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/pbimBl-6bwp","jetpack_featured_media_url":"https:\/\/bugaluu.com\/news\/wp-content\/uploads\/sites\/3\/2024\/06\/image_922875229-hRaU1v.jpeg","_links":{"self":[{"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/posts\/1474261","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/comments?post=1474261"}],"version-history":[{"count":0,"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/posts\/1474261\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/media\/1474262"}],"wp:attachment":[{"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/media?parent=1474261"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/categories?post=1474261"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/bugaluu.com\/news\/wp-json\/wp\/v2\/tags?post=1474261"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}