Detroit Lions running back Jahmyr Gibbs leads my Week 5 fantasy football running back rankings. File Photo by David Tulis\/UPI<\/p>\n
MIAMI, Oct. 1 (UPI) —<\/span> Jahmyr Gibbs and De’Von Achane lead my Top-50 fantasy football running back rankings for Week 5 of the 2025 season.<\/p>\n Jonathan Taylor, Saquon Barkley and Omarion Hampton join Gibbs and Achane inside my Top 5. James Cook, Ashton Jeanty, Derrick Henry, Travis Etienne and Javonte Williams are my other Top-10 options.<\/p>\n My Top 20 quarterback<\/a> and Top-50 wide receiver rankings for Week 5 can be found here<\/a>. My waiver-wire and free agent targets for Week 5 are available here<\/a>.<\/p>\n All of my positional rankings will be updated until Week 5 kickoffs. Players also will be moved out of or adjusted within the rankings based on injuries.<\/p>\n Be sure to monitor your lineups for injury developments. Players from the Atlanta Falcons, Chicago Bears, Green Bay Packers and Pittsburgh Steelers, who are on bye, should not be in starting lineups. San Francisco 49ers and Los Angeles Rams running backs, who played Thursday, were removed from my rankings.<\/p>\n Miami Dolphins running back De’Von Achane (C) is an elite fantasy football RB1. File Photo by Kevin M. Cox\/UPI<\/p>\n Week 5 running back rankings<\/p>\n 1. Jahmyr Gibbs, Detroit Lions at CIN<\/p>\n Minnesota Vikings running back Jordan Mason (L) can stay in lineups as a fantasy football RB2. File Photo by Mark Black\/UPI<\/p>\n 2. De’Von Achane, Miami Dolphins at CAR<\/p>\n 3. Jonathan Taylor, Indianapolis Colts vs. LV<\/p>\n San Francisco 49ers running back Christian McCaffrey is among my Top 5 fantasy football plays for Week 5. File Photo by Terry Schmitt\/UPI<\/p>\n 4. Saquon Barkley, Philadelphia Eagles vs. DEN<\/p>\n 5. Omarion Hampton, Los Angeles Chargers vs. WAS<\/p>\n Buffalo Bills running back James Cook is my No. 7 fantasy football running back in Week 5. File Photo by Rena Laverty\/UPI<\/p>\n 6. James Cook, Buffalo Bills vs. NE<\/p>\n 7. Ashton Jeanty, Las Vegas Raiders at IND<\/p>\n 8. Derrick Henry, Baltimore Ravens vs. HOU<\/p>\n 9. Travis Etienne, Jacksonville Jaguars vs. KC<\/p>\n 10. Javonte Williams, Dallas Cowboys at NYJ<\/p>\n 11. Quinshon Judkins, Cleveland Browns vs. MIN<\/p>\n 12. Breece Hall, New York Jets vs. DAL<\/p>\n 13. Cam Skattebo, New York Giants at NO<\/p>\n 14. J.K. Dobbins, Denver Broncos at PHI<\/p>\n 15. Alvin Kamara, New Orleans Saints vs. NYG<\/p>\n 16. Jordan Mason, Minnesota Vikings vs. CLE<\/p>\n 17. Chase Brown, Cincinnati Bengals vs. DET<\/p>\n 18. David Montgomery, Detroit Lions at CIN<\/p>\n 19. Kenneth Walker, Seattle Seahawks vs. TB<\/p>\n 20. Woody Marks, Houston Texans at BAL<\/p>\n 21. Tony Pollard, Tennessee Titans at ARI<\/p>\n 22. Rhamondre Stevenson, New England Patriots at BUF<\/p>\n 23. Emari Demercado, Arizona Cardinals vs. TEN<\/p>\n 24. R.J. Harvey, Denver Broncos at PHI<\/p>\n 25. Rico Dowdle, Carolina Panthers vs. MIA<\/p>\n 26. TreVeyon Henderson, New England Patriots at BUF<\/p>\n 27. Isiah Pacheco, Kansas City Chiefs at JAX<\/p>\n 28. Bucky Irving, Tampa Bay Buccaneers at SEA<\/p>\n 29. Zach Charbonnet, Seattle Seahawks vs. TB<\/p>\n 30. Rachaad White, Tampa Bay Buccaneers at SEA<\/p>\n 31. Michael Carter, Arizona Cardinals vs. TEN<\/p>\n 32. Bhayshul Tuten, Jacksonville Jaguars vs. KC<\/p>\n 33. Chris Rodriguez, Washington Commanders at LAC<\/p>\n 34. Nick Chubb, Houston Texans at BAL<\/p>\n 35. Justice Hill, Baltimore Ravens vs. HOU<\/p>\n 36. Jacory Croskey-Merritt, Washington Commanders at LAC<\/p>\n 37. Kendre Miller, New Orleans Saints vs. NYG<\/p>\n 38. Ollie Gordon II, Miami Dolphins at CAR<\/p>\n 39. Kareem Hunt, Kansas City Chiefs at JAX<\/p>\n 40. Zavier Scott, Minnesota Vikings vs. CLE<\/p>\n 41. Isaiah Davis, New York Jets vs. DAL<\/p>\n 42. Jerome Ford, Cleveland Browns vs. MIN<\/p>\n 43. Devin Singletary, New York Giants at NO<\/p>\n 44. Jeremy McNichols, Washington Commanders at LAC<\/p>\n 45. Raheem Mostert, Las Vegas Raiders at IND<\/p>\n 47. Ty Johnson, Buffalo Bills vs. NE<\/p>\n 48. Jaydon Blue, Dallas Cowboys at NYJ<\/p>\n 49. Brashard Smith, Kansas City Chiefs at JAX<\/p>\n 50. Antonio Gibson, New England Patriots at BUF<\/p>\n