Posted in Web Acute liver failure – Symptoms, diagnosis and treatment … January 28, 2021 Acute liver failure (ALF) is a rapid decline in hepatic function characterised by jaundice, coagulopathy (INR >1.5), and hepatic encephalopathy in patients with no evidence of prior liver disease. Trey C, Davidson CS. https://bestpractice.bmj.com/topics/en-gb/1010