A Programmable Dual-RNA–Guided DNA Endonuclease in Adaptive Bacterial Immunity Martin Jinek,1,2* Krzysztof Chylinski,3,4* Ines Fonfara,4 Michael Hauer,2† Jennifer A. Doudna,1,2,5,6‡ Emmanuelle Charpentier4‡ Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) systems
http://genetics.wustl.edu/bio5491/files/2013/03/Jinek-et.-al.-2012.pdf

