Posted in Web Common Anorectal Conditions: Part II. Lesions – American … January 28, 2021 Chronic solitary ulcer is usually associated with defecation disorders and often confused with or mistaken for rectal cancer. The lesion must be biopsied to make sure that it is not neoplastic. 31 … https://www.aafp.org/afp/2001/0701/p77.html