Long-Term Use of Proton Pump Inhibitors and Risk of Stomach Cancer …

January 25, 2026

Published in BMJ 2026; 392 (doi: 10.1136/bmj-2025-086384), this research examined whether long-term PPI use is associated with an increased risk of gastric adenocarcinoma. The findings suggest that long-term use of PPIs may not be linked to stomach cancer, offering important insights for patients and healthcare providers alike.

Long-Term Use of Proton Pump Inhibitors and Risk of Stomach Cancer … <body> <h1> Array ( [0] => kong-term use of proton pump inhibitors and risk of stomach cancer … [1] => pong-term use of proton pump inhibitors and risk of stomach cancer … [2] => oong-term use of proton pump inhibitors and risk of stomach cancer … [3] => ling-term use of proton pump inhibitors and risk of stomach cancer … [4] => lkng-term use of proton pump inhibitors and risk of stomach cancer … [5] => llng-term use of proton pump inhibitors and risk of stomach cancer … [6] => lpng-term use of proton pump inhibitors and risk of stomach cancer … [7] => l0ng-term use of proton pump inhibitors and risk of stomach cancer … [8] => l9ng-term use of proton pump inhibitors and risk of stomach cancer … [9] => lobg-term use of proton pump inhibitors and risk of stomach cancer … [10] => lomg-term use of proton pump inhibitors and risk of stomach cancer … [11] => lojg-term use of proton pump inhibitors and risk of stomach cancer … [12] => lohg-term use of proton pump inhibitors and risk of stomach cancer … [13] => lonf-term use of proton pump inhibitors and risk of stomach cancer … [14] => lonv-term use of proton pump inhibitors and risk of stomach cancer … [15] => lonb-term use of proton pump inhibitors and risk of stomach cancer … [16] => lonh-term use of proton pump inhibitors and risk of stomach cancer … [17] => lony-term use of proton pump inhibitors and risk of stomach cancer … [18] => lont-term use of proton pump inhibitors and risk of stomach cancer … [19] => long0term use of proton pump inhibitors and risk of stomach cancer … [20] => longpterm use of proton pump inhibitors and risk of stomach cancer … [21] => long-rerm use of proton pump inhibitors and risk of stomach cancer … [22] => long-ferm use of proton pump inhibitors and risk of stomach cancer … [23] => long-germ use of proton pump inhibitors and risk of stomach cancer … [24] => long-yerm use of proton pump inhibitors and risk of stomach cancer … [25] => long-6erm use of proton pump inhibitors and risk of stomach cancer … [26] => long-5erm use of proton pump inhibitors and risk of stomach cancer … [27] => long-twrm use of proton pump inhibitors and risk of stomach cancer … [28] => long-tsrm use of proton pump inhibitors and risk of stomach cancer … [29] => long-tdrm use of proton pump inhibitors and risk of stomach cancer … [30] => long-trrm use of proton pump inhibitors and risk of stomach cancer … [31] => long-t4rm use of proton pump inhibitors and risk of stomach cancer … [32] => long-t3rm use of proton pump inhibitors and risk of stomach cancer … [33] => long-teem use of proton pump inhibitors and risk of stomach cancer … [34] => long-tedm use of proton pump inhibitors and risk of stomach cancer … [35] => long-tefm use of proton pump inhibitors and risk of stomach cancer … [36] => long-tetm use of proton pump inhibitors and risk of stomach cancer … [37] => long-te5m use of proton pump inhibitors and risk of stomach cancer … [38] => long-te4m use of proton pump inhibitors and risk of stomach cancer … [39] => long-tern use of proton pump inhibitors and risk of stomach cancer … [40] => long-terk use of proton pump inhibitors and risk of stomach cancer … [41] => long-terj use of proton pump inhibitors and risk of stomach cancer … [42] => long-term yse of proton pump inhibitors and risk of stomach cancer … [43] => long-term hse of proton pump inhibitors and risk of stomach cancer … [44] => long-term jse of proton pump inhibitors and risk of stomach cancer … [45] => long-term ise of proton pump inhibitors and risk of stomach cancer … [46] => long-term 8se of proton pump inhibitors and risk of stomach cancer … [47] => long-term 7se of proton pump inhibitors and risk of stomach cancer … [48] => long-term uae of proton pump inhibitors and risk of stomach cancer … [49] => long-term uze of proton pump inhibitors and risk of stomach cancer … [50] => long-term uxe of proton pump inhibitors and risk of stomach cancer … [51] => long-term ude of proton pump inhibitors and risk of stomach cancer … [52] => long-term uee of proton pump inhibitors and risk of stomach cancer … [53] => long-term uwe of proton pump inhibitors and risk of stomach cancer … [54] => long-term usw of proton pump inhibitors and risk of stomach cancer … [55] => long-term uss of proton pump inhibitors and risk of stomach cancer … [56] => long-term usd of proton pump inhibitors and risk of stomach cancer … [57] => long-term usr of proton pump inhibitors and risk of stomach cancer … [58] => long-term us4 of proton pump inhibitors and risk of stomach cancer … [59] => long-term us3 of proton pump inhibitors and risk of stomach cancer … [60] => long-term use if proton pump inhibitors and risk of stomach cancer … [61] => long-term use kf proton pump inhibitors and risk of stomach cancer … [62] => long-term use lf proton pump inhibitors and risk of stomach cancer … [63] => long-term use pf proton pump inhibitors and risk of stomach cancer … [64] => long-term use 0f proton pump inhibitors and risk of stomach cancer … [65] => long-term use 9f proton pump inhibitors and risk of stomach cancer … [66] => long-term use od proton pump inhibitors and risk of stomach cancer … [67] => long-term use oc proton pump inhibitors and risk of stomach cancer … [68] => long-term use ov proton pump inhibitors and risk of stomach cancer … [69] => long-term use og proton pump inhibitors and risk of stomach cancer … [70] => long-term use ot proton pump inhibitors and risk of stomach cancer … [71] => long-term use or proton pump inhibitors and risk of stomach cancer … [72] => long-term use of oroton pump inhibitors and risk of stomach cancer … [73] => long-term use of lroton pump inhibitors and risk of stomach cancer … [74] => long-term use of -roton pump inhibitors and risk of stomach cancer … [75] => long-term use of 0roton pump inhibitors and risk of stomach cancer … [76] => long-term use of peoton pump inhibitors and risk of stomach cancer … [77] => long-term use of pdoton pump inhibitors and risk of stomach cancer … [78] => long-term use of pfoton pump inhibitors and risk of stomach cancer … [79] => long-term use of ptoton pump inhibitors and risk of stomach cancer … [80] => long-term use of p5oton pump inhibitors and risk of stomach cancer … [81] => long-term use of p4oton pump inhibitors and risk of stomach cancer … [82] => long-term use of priton pump inhibitors and risk of stomach cancer … [83] => long-term use of prkton pump inhibitors and risk of stomach cancer … [84] => long-term use of prlton pump inhibitors and risk of stomach cancer … [85] => long-term use of prpton pump inhibitors and risk of stomach cancer … [86] => long-term use of pr0ton pump inhibitors and risk of stomach cancer … [87] => long-term use of pr9ton pump inhibitors and risk of stomach cancer … [88] => long-term use of proron pump inhibitors and risk of stomach cancer … [89] => long-term use of profon pump inhibitors and risk of stomach cancer … [90] => long-term use of progon pump inhibitors and risk of stomach cancer … [91] => long-term use of proyon pump inhibitors and risk of stomach cancer … [92] => long-term use of pro6on pump inhibitors and risk of stomach cancer … [93] => long-term use of pro5on pump inhibitors and risk of stomach cancer … [94] => long-term use of protin pump inhibitors and risk of stomach cancer … [95] => long-term use of protkn pump inhibitors and risk of stomach cancer … [96] => long-term use of protln pump inhibitors and risk of stomach cancer … [97] => long-term use of protpn pump inhibitors and risk of stomach cancer … [98] => long-term use of prot0n pump inhibitors and risk of stomach cancer … [99] => long-term use of prot9n pump inhibitors and risk of stomach cancer … [100] => long-term use of protob pump inhibitors and risk of stomach cancer … [101] => long-term use of protom pump inhibitors and risk of stomach cancer … [102] => long-term use of protoj pump inhibitors and risk of stomach cancer … [103] => long-term use of protoh pump inhibitors and risk of stomach cancer … [104] => long-term use of proton oump inhibitors and risk of stomach cancer … [105] => long-term use of proton lump inhibitors and risk of stomach cancer … [106] => long-term use of proton -ump inhibitors and risk of stomach cancer … [107] => long-term use of proton 0ump inhibitors and risk of stomach cancer … [108] => long-term use of proton pymp inhibitors and risk of stomach cancer … [109] => long-term use of proton phmp inhibitors and risk of stomach cancer … [110] => long-term use of proton pjmp inhibitors and risk of stomach cancer … [111] => long-term use of proton pimp inhibitors and risk of stomach cancer … [112] => long-term use of proton p8mp inhibitors and risk of stomach cancer … [113] => long-term use of proton p7mp inhibitors and risk of stomach cancer … [114] => long-term use of proton punp inhibitors and risk of stomach cancer … [115] => long-term use of proton pukp inhibitors and risk of stomach cancer … [116] => long-term use of proton pujp inhibitors and risk of stomach cancer … [117] => long-term use of proton pumo inhibitors and risk of stomach cancer … [118] => long-term use of proton puml inhibitors and risk of stomach cancer … [119] => long-term use of proton pum- inhibitors and risk of stomach cancer … [120] => long-term use of proton pum0 inhibitors and risk of stomach cancer … [121] => long-term use of proton pump unhibitors and risk of stomach cancer … [122] => long-term use of proton pump jnhibitors and risk of stomach cancer … [123] => long-term use of proton pump knhibitors and risk of stomach cancer … [124] => long-term use of proton pump onhibitors and risk of stomach cancer … [125] => long-term use of proton pump 9nhibitors and risk of stomach cancer … [126] => long-term use of proton pump 8nhibitors and risk of stomach cancer … [127] => long-term use of proton pump ibhibitors and risk of stomach cancer … [128] => long-term use of proton pump imhibitors and risk of stomach cancer … [129] => long-term use of proton pump ijhibitors and risk of stomach cancer … [130] => long-term use of proton pump ihhibitors and risk of stomach cancer … [131] => long-term use of proton pump ingibitors and risk of stomach cancer … [132] => long-term use of proton pump inbibitors and risk of stomach cancer … [133] => long-term use of proton pump innibitors and risk of stomach cancer … [134] => long-term use of proton pump injibitors and risk of stomach cancer … [135] => long-term use of proton pump inuibitors and risk of stomach cancer … [136] => long-term use of proton pump inyibitors and risk of stomach cancer … [137] => long-term use of proton pump inhubitors and risk of stomach cancer … [138] => long-term use of proton pump inhjbitors and risk of stomach cancer … [139] => long-term use of proton pump inhkbitors and risk of stomach cancer … [140] => long-term use of proton pump inhobitors and risk of stomach cancer … [141] => long-term use of proton pump inh9bitors and risk of stomach cancer … [142] => long-term use of proton pump inh8bitors and risk of stomach cancer … [143] => long-term use of proton pump inhivitors and risk of stomach cancer … [144] => long-term use of proton pump inhinitors and risk of stomach cancer … [145] => long-term use of proton pump inhihitors and risk of stomach cancer … [146] => long-term use of proton pump inhigitors and risk of stomach cancer … [147] => long-term use of proton pump inhibutors and risk of stomach cancer … [148] => long-term use of proton pump inhibjtors and risk of stomach cancer … [149] => long-term use of proton pump inhibktors and risk of stomach cancer … [150] => long-term use of proton pump inhibotors and risk of stomach cancer … [151] => long-term use of proton pump inhib9tors and risk of stomach cancer … [152] => long-term use of proton pump inhib8tors and risk of stomach cancer … [153] => long-term use of proton pump inhibirors and risk of stomach cancer … [154] => long-term use of proton pump inhibifors and risk of stomach cancer … [155] => long-term use of proton pump inhibigors and risk of stomach cancer … [156] => long-term use of proton pump inhibiyors and risk of stomach cancer … [157] => long-term use of proton pump inhibi6ors and risk of stomach cancer … [158] => long-term use of proton pump inhibi5ors and risk of stomach cancer … [159] => long-term use of proton pump inhibitirs and risk of stomach cancer … [160] => long-term use of proton pump inhibitkrs and risk of stomach cancer … [161] => long-term use of proton pump inhibitlrs and risk of stomach cancer … [162] => long-term use of proton pump inhibitprs and risk of stomach cancer … [163] => long-term use of proton pump inhibit0rs and risk of stomach cancer … [164] => long-term use of proton pump inhibit9rs and risk of stomach cancer … [165] => long-term use of proton pump inhibitoes and risk of stomach cancer … [166] => long-term use of proton pump inhibitods and risk of stomach cancer … [167] => long-term use of proton pump inhibitofs and risk of stomach cancer … [168] => long-term use of proton pump inhibitots and risk of stomach cancer … [169] => long-term use of proton pump inhibito5s and risk of stomach cancer … [170] => long-term use of proton pump inhibito4s and risk of stomach cancer … [171] => long-term use of proton pump inhibitora and risk of stomach cancer … [172] => long-term use of proton pump inhibitorz and risk of stomach cancer … [173] => long-term use of proton pump inhibitorx and risk of stomach cancer … [174] => long-term use of proton pump inhibitord and risk of stomach cancer … [175] => long-term use of proton pump inhibitore and risk of stomach cancer … [176] => long-term use of proton pump inhibitorw and risk of stomach cancer … [177] => long-term use of proton pump inhibitors znd risk of stomach cancer … [178] => long-term use of proton pump inhibitors snd risk of stomach cancer … [179] => long-term use of proton pump inhibitors wnd risk of stomach cancer … [180] => long-term use of proton pump inhibitors qnd risk of stomach cancer … [181] => long-term use of proton pump inhibitors abd risk of stomach cancer … [182] => long-term use of proton pump inhibitors amd risk of stomach cancer … [183] => long-term use of proton pump inhibitors ajd risk of stomach cancer … [184] => long-term use of proton pump inhibitors ahd risk of stomach cancer … [185] => long-term use of proton pump inhibitors ans risk of stomach cancer … [186] => long-term use of proton pump inhibitors anx risk of stomach cancer … [187] => long-term use of proton pump inhibitors anc risk of stomach cancer … [188] => long-term use of proton pump inhibitors anf risk of stomach cancer … [189] => long-term use of proton pump inhibitors anr risk of stomach cancer … [190] => long-term use of proton pump inhibitors ane risk of stomach cancer … [191] => long-term use of proton pump inhibitors and eisk of stomach cancer … [192] => long-term use of proton pump inhibitors and disk of stomach cancer … [193] => long-term use of proton pump inhibitors and fisk of stomach cancer … [194] => long-term use of proton pump inhibitors and tisk of stomach cancer … [195] => long-term use of proton pump inhibitors and 5isk of stomach cancer … [196] => long-term use of proton pump inhibitors and 4isk of stomach cancer … [197] => long-term use of proton pump inhibitors and rusk of stomach cancer … [198] => long-term use of proton pump inhibitors and rjsk of stomach cancer … [199] => long-term use of proton pump inhibitors and rksk of stomach cancer … [200] => long-term use of proton pump inhibitors and rosk of stomach cancer … [201] => long-term use of proton pump inhibitors and r9sk of stomach cancer … [202] => long-term use of proton pump inhibitors and r8sk of stomach cancer … [203] => long-term use of proton pump inhibitors and riak of stomach cancer … [204] => long-term use of proton pump inhibitors and rizk of stomach cancer … [205] => long-term use of proton pump inhibitors and rixk of stomach cancer … [206] => long-term use of proton pump inhibitors and ridk of stomach cancer … [207] => long-term use of proton pump inhibitors and riek of stomach cancer … [208] => long-term use of proton pump inhibitors and riwk of stomach cancer … [209] => long-term use of proton pump inhibitors and risj of stomach cancer … [210] => long-term use of proton pump inhibitors and rism of stomach cancer … [211] => long-term use of proton pump inhibitors and risl of stomach cancer … [212] => long-term use of proton pump inhibitors and riso of stomach cancer … [213] => long-term use of proton pump inhibitors and risi of stomach cancer … [214] => long-term use of proton pump inhibitors and risk if stomach cancer … [215] => long-term use of proton pump inhibitors and risk kf stomach cancer … [216] => long-term use of proton pump inhibitors and risk lf stomach cancer … [217] => long-term use of proton pump inhibitors and risk pf stomach cancer … [218] => long-term use of proton pump inhibitors and risk 0f stomach cancer … [219] => long-term use of proton pump inhibitors and risk 9f stomach cancer … [220] => long-term use of proton pump inhibitors and risk od stomach cancer … [221] => long-term use of proton pump inhibitors and risk oc stomach cancer … [222] => long-term use of proton pump inhibitors and risk ov stomach cancer … [223] => long-term use of proton pump inhibitors and risk og stomach cancer … [224] => long-term use of proton pump inhibitors and risk ot stomach cancer … [225] => long-term use of proton pump inhibitors and risk or stomach cancer … [226] => long-term use of proton pump inhibitors and risk of atomach cancer … [227] => long-term use of proton pump inhibitors and risk of ztomach cancer … [228] => long-term use of proton pump inhibitors and risk of xtomach cancer … [229] => long-term use of proton pump inhibitors and risk of dtomach cancer … [230] => long-term use of proton pump inhibitors and risk of etomach cancer … [231] => long-term use of proton pump inhibitors and risk of wtomach cancer … [232] => long-term use of proton pump inhibitors and risk of sromach cancer … [233] => long-term use of proton pump inhibitors and risk of sfomach cancer … [234] => long-term use of proton pump inhibitors and risk of sgomach cancer … [235] => long-term use of proton pump inhibitors and risk of syomach cancer … [236] => long-term use of proton pump inhibitors and risk of s6omach cancer … [237] => long-term use of proton pump inhibitors and risk of s5omach cancer … [238] => long-term use of proton pump inhibitors and risk of stimach cancer … [239] => long-term use of proton pump inhibitors and risk of stkmach cancer … [240] => long-term use of proton pump inhibitors and risk of stlmach cancer … [241] => long-term use of proton pump inhibitors and risk of stpmach cancer … [242] => long-term use of proton pump inhibitors and risk of st0mach cancer … [243] => long-term use of proton pump inhibitors and risk of st9mach cancer … [244] => long-term use of proton pump inhibitors and risk of stonach cancer … [245] => long-term use of proton pump inhibitors and risk of stokach cancer … [246] => long-term use of proton pump inhibitors and risk of stojach cancer … [247] => long-term use of proton pump inhibitors and risk of stomzch cancer … [248] => long-term use of proton pump inhibitors and risk of stomsch cancer … [249] => long-term use of proton pump inhibitors and risk of stomwch cancer … [250] => long-term use of proton pump inhibitors and risk of stomqch cancer … [251] => long-term use of proton pump inhibitors and risk of stomaxh cancer … [252] => long-term use of proton pump inhibitors and risk of stomavh cancer … [253] => long-term use of proton pump inhibitors and risk of stomafh cancer … [254] => long-term use of proton pump inhibitors and risk of stomadh cancer … [255] => long-term use of proton pump inhibitors and risk of stomacg cancer … [256] => long-term use of proton pump inhibitors and risk of stomacb cancer … [257] => long-term use of proton pump inhibitors and risk of stomacn cancer … [258] => long-term use of proton pump inhibitors and risk of stomacj cancer … [259] => long-term use of proton pump inhibitors and risk of stomacu cancer … [260] => long-term use of proton pump inhibitors and risk of stomacy cancer … [261] => long-term use of proton pump inhibitors and risk of stomach xancer … [262] => long-term use of proton pump inhibitors and risk of stomach vancer … [263] => long-term use of proton pump inhibitors and risk of stomach fancer … [264] => long-term use of proton pump inhibitors and risk of stomach dancer … [265] => long-term use of proton pump inhibitors and risk of stomach czncer … [266] => long-term use of proton pump inhibitors and risk of stomach csncer … [267] => long-term use of proton pump inhibitors and risk of stomach cwncer … [268] => long-term use of proton pump inhibitors and risk of stomach cqncer … [269] => long-term use of proton pump inhibitors and risk of stomach cabcer … [270] => long-term use of proton pump inhibitors and risk of stomach camcer … [271] => long-term use of proton pump inhibitors and risk of stomach cajcer … [272] => long-term use of proton pump inhibitors and risk of stomach cahcer … [273] => long-term use of proton pump inhibitors and risk of stomach canxer … [274] => long-term use of proton pump inhibitors and risk of stomach canver … [275] => long-term use of proton pump inhibitors and risk of stomach canfer … [276] => long-term use of proton pump inhibitors and risk of stomach cander … [277] => long-term use of proton pump inhibitors and risk of stomach cancwr … [278] => long-term use of proton pump inhibitors and risk of stomach cancsr … [279] => long-term use of proton pump inhibitors and risk of stomach cancdr … [280] => long-term use of proton pump inhibitors and risk of stomach cancrr … [281] => long-term use of proton pump inhibitors and risk of stomach canc4r … [282] => long-term use of proton pump inhibitors and risk of stomach canc3r … [283] => long-term use of proton pump inhibitors and risk of stomach cancee … [284] => long-term use of proton pump inhibitors and risk of stomach canced … [285] => long-term use of proton pump inhibitors and risk of stomach cancef … [286] => long-term use of proton pump inhibitors and risk of stomach cancet … [287] => long-term use of proton pump inhibitors and risk of stomach cance5 … [288] => long-term use of proton pump inhibitors and risk of stomach cance4 … ) https://clipperroutesevere.com/kdjbw4ywu?key=a54852e5dee5f9fa314d768d692142d1 </h1> </body>