The LSU Tigers and Clemson Tigers take the field Monday, January 13, at 8:00 p.m. ET in the College Football Playoff National Championship.. LSU vs. Clemson Odds and Betting Lines. LSU is favored by 5.5 points over Clemson, who is the defending National Champions.BetMGM oddsmakers are expecting a high-scoring affair, with the Over/Under set at 69.5 points.

