Troubleshoot connecting to Amazon S3 from VPC endpoints

Important: Endpoints currently don’t support cross-Region requests. Be sure that your endpoint is in the same Region as your bucket. You can use the get-bucket-location command to find the location of your bucket.. Open the Amazon VPC console.; In the navigation pane, under Virtual Private Cloud, choose Endpoints.; In the resource list, choose the endpoint associated with the VPC subnet that …

https://aws.amazon.com/premiumsupport/knowledge-center/connect-s3-vpc-endpoint/